Deal Library / Pharma BD Deal Intelligence

Pharma Deals of 2022

The Pharma Closeout tracks 211 deals, $158.5B in disclosed deal value, 22 with a post-close Outcome Score for the year 2022.

Median Critic Score: 83  ·  Median Outcome Score: 62

Best outcome: Merck & Co. Inc. / Moderna, Inc. (86)  ·  Weakest outcome: Pfizer Inc. / Global Blood Therapeutics Inc. (29)

All 211 deals

• Merck & Co. Inc. / Moderna, Inc. — 2022 · $250M · Worked — the deal delivered on its rationale.
• Takeda Pharmaceutical Company Ltd. / Nimbus Lakshmi — 2022 · $6.0B · Worked — the deal delivered on its rationale.
• Johnson & Johnson / Abiomed Inc. — 2022 · $16.6B · Largely worked — most objectives met.
• Amgen Inc. / Horizon Therapeutics plc — 2022 · $27.8B · Largely worked — most objectives met.
• Biocon Biologics Ltd. / Viatris Biosimilars Business — 2022 · $3.0B · Largely worked — most objectives met.
• GSK plc / Sierra Oncology Inc. — 2022 · $1.9B · Largely worked — most objectives met.
• Bristol-Myers Squibb Company / Turning Point Therapeutics Inc. — 2022 · $4.1B · Largely worked — most objectives met.
• Pfizer Inc. / Biohaven Pharmaceutical Holding Company Ltd. — 2022 · $11.6B · Largely worked — most objectives met.
• Roche Holding AG / Repare Therapeutics Inc. — 2022 · $1.3B · Largely worked — most objectives met.
• Novo Nordisk A/S / Forma Therapeutics Holdings Inc. — 2022 · $1.1B · Largely worked — most objectives met.
• Pfizer Inc. / Beam Therapeutics Inc. — 2022 · $1.4B · Largely worked — most objectives met.
• AstraZeneca PLC / TeneoTwo Inc. — 2022 · $1.3B · Largely worked — most objectives met.
• Amgen Inc. / ChemoCentryx Inc. — 2022 · $3.7B · Largely worked — most objectives met.
• Vertex Pharmaceuticals Incorporated / ViaCyte Inc. — 2022 · $320M · Largely worked — most objectives met.
• Merck & Co. Inc. / Imago BioSciences Inc. — 2022 · $1.4B · Largely worked — most objectives met.
• Merck & Co. Inc. / Kelun-Biotech Biopharmaceuticals Co. Ltd. — 2022 · $936M · Largely worked — most objectives met.
• Sumitovant Biopharma / Myovant Sciences Ltd. — 2022 · $1.7B · Largely worked — most objectives met.
• Novo Nordisk A/S / Forma Therapeutics Holdings Inc. — 2022 · $1.1B · Mixed — partial payoff, real shortfalls.
• Viatris / Oyster Point Pharma, Inc. — 2022 · $299M · Mixed — partial payoff, real shortfalls.
• AstraZeneca PLC / TeneoTwo Inc. — 2022 · $1.3B · Mixed — partial payoff, real shortfalls.
• GSK plc / Affinivax Inc. — 2022 · $3.3B · Mixed — partial payoff, real shortfalls.
• Pfizer Inc. / Global Blood Therapeutics Inc. — 2022 · $5.4B · Did not work — the deal failed to deliver.
• Takeda Pharmaceutical Company Ltd. / Nimbus Therapeutics (Lakshmi subsidiary, TYK2 program) — 2022 · $6.0B
• Oculis S.A. / Accure Therapeutics — 2022
• Sciwind Biosciences / SynerK — 2022
• Menarini Group / NewAmsterdam Pharma — 2022
• RNAGENE Inc. / PharmAbcine Inc. — 2022
• Orion Biotechnology Canada Ltd / Peptilogics — 2022
• Recordati S.p.A. / EUSA Pharma (UK) Ltd. — 2022 · $845M
• Bristol-Myers Squibb Company / Century Therapeutics Inc. — 2022 · $3.1B
• NextCure, Inc. / LegoChem Biosciences, Inc. — 2022
• Full-Life Technologies / Focus-X Therapeutics — 2022
• Bristol-Myers Squibb Company / Immatics N.V. — 2022 · $770M
• VBI Vaccines Inc. / Agenus — 2022
• BioNTech SE / MediGene AG — 2022
• Hikma Pharmaceuticals PLC / Shanghai Junshi Biosciences Co., Ltd. — 2022
• Sato Pharmaceutical Co., Ltd. / EPI Health, LLC — 2022
• Sanofi SA / Exscientia plc — 2022 · $5.3B
• Gaelan Medical Trade LLC / RedHill Biopharma Ltd. — 2022
• Bristol Myers Squibb / BridgeBio Pharma, Inc. — 2022 · $905M
• Immunocore Holdings Plc / Sanofi — 2022
• Ultragenyx Pharmaceutical Inc. / Abeona Therapeutics Inc. — 2022
• Ono Pharmaceutical Co., Ltd. / Captor Therapeutics S.A. — 2022
• AstraZeneca PLC / LogicBio Therapeutics Inc. — 2022 · $70M
• BioAtla, Inc. / Bristol Myers Squibb — 2022
• Merck KGaA, Darmstadt, Germany / Mersana Therapeutics, Inc. — 2022
• Seagen Inc. / LAVA Therapeutics N.V. — 2022
• Sanofi SA / Innate Pharma SA — 2022 · $1.4B
• Olema Pharmaceuticals, Inc. / Aurigene Discovery Technologies Limited — 2022
• Regeneron Pharmaceuticals, Inc. / Sanofi S.A. (Libtayo global rights) — 2022 · $1.1B
• Pyxis Oncology / Biosion, Inc. — 2022
• Eli Lilly and Company / Abbisko Therapeutics Co., Ltd. — 2022
• Pasithea Therapeutics Corp. / AlloMek Therapeutics, LLC — 2022
• Taiho Pharmaceutical Co., Ltd. / Cullinan Oncology, Inc. — 2022
• Global Cord Blood Corporation / Cellenkos, Inc. — 2022
• Novan, Inc. / EPI Health, LLC — 2022
• Merck & Co. Inc. / Moderna Inc. (mRNA-4157/V940 option exercise) — 2022 · $250M
• Janssen Biotech, Inc. / Mersana Therapeutics, Inc. — 2022
• Assertio Holdings, Inc. / Aquestive Therapeutics, Inc. — 2022
• Sumitomo Pharma / Sumitovant Biopharma / Myovant Sciences Ltd. — 2022 · $1.7B
• Vertex Pharmaceuticals Incorporated / Verve Therapeutics, Inc. — 2022
• Mirati Therapeutics, Inc. / Aadi Bioscience, Inc. — 2022
• Genentech / Kiniksa Pharmaceuticals, Ltd. — 2022
• Nestlé Health Science / Enterome — 2022
• Astellas Pharma Inc. / GO Therapeutics, Inc. — 2022
• Ipsen / Marengo Therapeutics, Inc. — 2022
• Healx / Ovid Therapeutics — 2022
• Roche / Adagene Inc. — 2022
• Simcere / Lynk Pharmaceuticals Co., Ltd. — 2022
• Actinium Pharmaceuticals, Inc. / EpicentRx, Inc. — 2022
• Mitsubishi Tanabe Pharma Corporation / EditForce, Inc. — 2022
• ABL Bio Inc. / Sanofi S.A. (ABL301 license to Sanofi) — 2022 · $1.1B
• Sanwa Kagaku Kenkyusho Co., Ltd. / Crinetics Pharmaceuticals, Inc. — 2022
• Grifols / Endpoint Health, Inc. — 2022
• Io Biotech / Merck & Co. Inc. — 2022
• Syncona Limited / Applied Genetic Technologies Corporation — 2022 · $24M
• Regeneron Pharmaceuticals, Inc. / CytomX Therapeutics, Inc. — 2022
• Psyence Group Inc. / Filament Health Corp. — 2022
• Astellas Pharma Inc. / Generian Pharmaceuticals, Inc. — 2022
• AUM Biosciences / Roche — 2022
• OnCusp Therapeutics / Multitude Therapeutics — 2022
• AbbVie Inc. / DJS Antibodies Ltd. — 2022 · $255M
• Roche Holding AG / Poseida Therapeutics — 2022 · $6.1B
• SERB Pharmaceuticals / Soligenix — 2022
• Pediatrix Therapeutics, Inc. / Aclaris Therapeutics, Inc. — 2022
• Sanofi SA / IGM Biosciences Inc. — 2022 · $6.2B
• SIGA Technologies, Inc. / KaliVir Immunotherapeutics — 2022
• CSL Limited / Arcturus Therapeutics Holdings Inc — 2022
• Brickell Biotech, Inc. / Carna Biosciences, Inc. — 2022
• Sanofi SA / Adagene Inc. — 2022 · $2.5B
• Antengene Corporation Limited / Celularity Inc — 2022
• SciNeuro Pharmaceuticals / GlaxoSmithKline — 2022
• Arctic Therapeutics International / Nacuity Pharmaceuticals, Inc. — 2022
• Biogen Inc. / Alectos Therapeutics Inc. — 2022
• Blueprint Medicines Corporation / Proteovant Therapeutics — 2022
• CARTEXELL / Integral Molecular — 2022
• Bristol Myers Squibb / SyntheX, Inc. — 2022
• AstraZeneca PLC / Neogene Therapeutics B.V. — 2022 · $320M
• Optimeos Life Sciences / Integral Molecular — 2022
• Roche / PRISM BioLab — 2022
• Jazz Pharmaceuticals plc / Zymeworks Inc. — 2022 · $1.8B
• Eli Lilly and Company / Nimbus Therapeutics LLC — 2022 · $496M
• Sernova Corp. / Evotec SE — 2022
• Panbela Therapeutics, Inc. / Cancer Prevention Pharmaceuticals, Inc. — 2022
• Astellas Pharma Inc. / Genetic Leap — 2022
• UCB S.A. / Zogenix Inc. — 2022 · $1.9B
• Pfizer Inc. / Voyager Therapeutics Inc. — 2022
• Amgen / Plexium, Inc. — 2022
• Novartis AG / Voyager Therapeutics Inc. — 2022 · $1.8B
• Eli Lilly and Company / Entos Pharmaceuticals — 2022
• Roche / Jnana Therapeutics — 2022
• Merck & Co. Inc. / Curve Therapeutics — 2022
• SIGA Technologies, Inc. / Bioarchitech — 2022
• Pfizer Inc. / Valneva SE (VLA15 collaboration update) — 2022 · $363M
• Sobi / ADC Therapeutics S.A. — 2022
• MedC Biopharma / A2W Pharma — 2022
• Sanofi SA / Atomwise Inc. — 2022 · $1.0B
• BioNTech SE / Matinas BioPharma — 2022
• Neuron23 / QIAGEN — 2022
• Bayer AG / Mammoth Biosciences Inc. — 2022 · $1.0B
• Vanda Pharmaceuticals Inc. / OliPass Corporation — 2022
• Allogene Therapeutics, Inc. / Antion Biosciences — 2022
• Merck & Co. Inc. / Nykode Therapeutics ASA — 2022
• AbbVie Inc. / Sosei Group Corp. (Sosei Heptares) — 2022 · $1.3B
• HUTCHMED (China) Limited / Genetron Holdings Limited — 2022
• Shanghai Fosun Pharmaceutical (Group) Co., Ltd. / Insilico Medicine — 2022
• Eli Lilly and Company / Sosei Group Corp. (Sosei Heptares) — 2022 · $730M
• Shenzhen IONOVA Life Science Co., Ltd. / Merck & Co. Inc. — 2022
• Genome and Company / Merck & Co. Inc. — 2022
• Immatics N.V. / Editas Medicine, Inc. — 2022
• Hyphens Pharma Pte. Ltd. / Cassiopea S.p.A. — 2022
• Jazz Pharmaceuticals plc / Sumitomo Pharma Co., Ltd. — 2022
• Akeso Inc. / Shenzhen Chipscreen Biosciences, Ltd. — 2022
• UCB / Praxis Precision Medicines, Inc. — 2022 · $100M
• Aculys Pharma, Inc. / Neurelis, Inc. — 2022
• ADVANZ PHARMA Corp. / PolyPid Ltd. — 2022
• invoX Pharma / F-star Therapeutics, Inc. — 2022
• Vertex Pharmaceuticals / SiteOne Therapeutics, Inc. — 2022
• Clearmind Medicine Inc. / SciSparc Ltd. — 2022
• GSK plc / Spero Therapeutics, Inc. — 2022 · $600M
• Hansoh Pharmaceuticals / Biotheus Inc. — 2022
• Lantheus Holdings, Inc. / POINT Biopharma Global Inc. — 2022
• Cabaletta Bio, Inc. / IASO Biotherapeutics — 2022 · $162M
• Caladrius Biosciences, Inc. / Cend Therapeutics, Inc. — 2022
• Shanghai Junshi Biociences Co., Ltd / DotBio Pte. Ltd — 2022
• IDEAYA Biosciences, Inc. / Amgen Inc. — 2022
• Blackstone Life Sciences / Sanofi S.A. (Sarclisa subQ co-development) — 2022 · $331M
• ONK Therapeutics Ltd. / Intellia Therapeutics, Inc. — 2022
• Tonix Pharmaceuticals Holding Corp. / Curia Global, Inc. — 2022
• Sanofi SA / Skyhawk Therapeutics Inc. — 2022 · $2.1B
• Sentynl Therapeutics, Inc. / BridgeBio Pharma, Inc. — 2022
• Pasithea Therapeutics Corp. / Alpha-5 integrin, LLC — 2022 · $4M
• Kallyope / Sosei Group Corporation — 2022
• Vividion Therapeutics, Inc. / Tavros Therapeutics, Inc. — 2022
• Zhongze Therapeutics / Digestome Therapeutics — 2022
• TRPharm / Foresee Pharmaceuticals Co., Ltd. — 2022
• Sanofi SA / Insilico Medicine Inc. — 2022 · $1.2B
• Kyverna Therapeutics / Intellia Therapeutics, Inc. — 2022
• Accord Healthcare, Ltd. / Myovant Sciences — 2022
• Antengene Corporation Limited / BeiGene — 2022
• Novo Nordisk A/S / Zealand Pharma A/S — 2022
• BioNTech SE / Ryvu Therapeutics S.A. — 2022
• Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd / Intravacc B.V. — 2022
• Takeda Pharmaceutical Company Limited / Adaptate Biotherapeutics — 2022
• OPKO Health, Inc. / ModeX Therapeutics, Inc. — 2022
• BridgeBio Pharma, Inc. / Amgen Inc. — 2022
• Innoviva, Inc. / Entasis Therapeutics Holdings Inc. — 2022
• iBio, Inc. / RubrYc Therapeutics, Inc. — 2022
• Prime Medicine Inc. / Myeloid Therapeutics, Inc. — 2022
• Daiichi Sankyo Company, Limited / ViGeneron GmbH — 2022
• Pfizer Inc. / BioNTech SE — 2022
• Sanofi / Salipro Biotech AB — 2022
• Transcenta Holding Limited / Bristol Myers Squibb — 2022
• Actinium Pharmaceuticals, Inc. / AVEO Oncology — 2022
• Janssen Pharmaceutica NV / Remix Therapeutics — 2022 · $1.0B
• Chugai Pharmaceutical Co. Ltd. / Halozyme Therapeutics, Inc. — 2022
• Scilex Holding Company / Romeg Therapeutics, LLC — 2022
• IGM Biosciences Inc. / ADC Therapeutics S.A. — 2022
• Merck KGaA, Darmstadt, Germany / F-star Therapeutics, Inc. — 2022
• Qilu Pharma / CellOrigin Biotech (Hangzhou) Co., Ltd. — 2022
• Odeon Therapeutics / OBI Pharma, Inc — 2022
• Taisho Pharmaceutical Co., Ltd. / Elixirgen Therapeutics, Inc. — 2022
• Regeneron Pharmaceuticals, Inc. / ViGeneron GmbH — 2022
• Amgen / Generate Biomedicines, Inc. — 2022 · $1.9B
• Affimed N.V. / Artiva Biotherapeutics, Inc. — 2022
• Sarepta Therapeutics Inc. / GenEdit, Inc. — 2022
• Cybin Inc. / Mindset Pharma Inc. — 2022
• AstraZeneca PLC / Neurimmune AG (NI006 license) — 2022 · $760M
• Pfizer Inc. / ReViral Ltd. — 2022 · $525M
• Boehringer Ingelheim / Surrozen, Inc. — 2022
• Danuo Science Group / Enosi Therapeutics — 2022
• AbbVie Inc. / Syndesi Therapeutics SA — 2022 · $1.0B
• Bridge Biotherapeutics / CellionBioMed — 2022
• SELLAS Life Sciences Group, Inc. / GenFleet Therapeutics (Shanghai), Inc. — 2022
• Huadong Medicine Co., Ltd. / Kiniksa Pharmaceuticals, Ltd. — 2022
• GenFleet Therapeutics / BioLineRx, Ltd. — 2022
• Indivior PLC / Opiant Pharmaceuticals Inc. — 2022
• SK Biopharmaceuticals / Biorchestra — 2022
• GSK plc / Wave Life Sciences Ltd. — 2022
• Shanghai KangaBio Co., Ltd. / Sanyou Biopharmaceuticals (Shanghai) Co., Ltd. — 2022
• Unison Medicines Inc / Vernalis Research — 2022
• GSK plc / Mersana Therapeutics, Inc. — 2022
• Merck & Co. Inc. / Orna Therapeutics, Inc. — 2022 · $3.6B
• Midatech Pharma plc / Bioasis Technologies Inc. — 2022
• Ipsen S.A. / Epizyme Inc. — 2022 · $247M
• Emergence Therapeutics AG / Synaffix B.V. — 2022 · $360M
• PCI Biotech / MDimune Inc. — 2022
• Amgen / Arrakis Therapeutics, Inc. — 2022
• EQRx / Insilico Medicine — 2022
• Optifye Therapeutics AG / DelSiTech Ltd — 2022
• Eli Lilly and Company / Akouos Inc. — 2022 · $610M

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