Pharma BD Deal Intelligence

Roche Holding AG / Poseida Therapeutics

2022 · Co-Development · $6.1B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Aug 04, 2022 BioPharma Dive Neutral

Poseida Therapeutics on Thursday signed a strategic global collaboration with Roche to develop and commercialize allogeneic CAR-T cell therapies, in a deal…

Aug 04, 2022 STAT News Bullish

Roche has agreed to pay Poseida Therapeutics up to $6 billion in upfront, equity, and milestone payments for global rights to develop and commercialize the…

Jan 08, 2025 SEC EDGAR (Poseida 8-K) Neutral

Poseida 8-K (Jan 2025): completion of merger with Blue Giant Acquisition Corp., Roche subsidiary; shares converted to right to receive $9.00 plus CVR; Poseida…

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In August 2022, Poseida Therapeutics and Roche entered a strategic global collaboration on allogeneic (off-the-shelf) CAR-T therapies for hematologic malignancies including multiple myeloma and B-cell lymphomas. Roche paid $110M upfront (plus a ~$50M equity investment) and committed up to ~$6B in development, regulatory and commercial milestones, with tiered royalties. Lead programs were P-BCMA-ALLO1 (allogeneic BCMA CAR-T) and P-CD19CD20-ALLO1. The partnership matured and expanded through 2024, with Poseida receiving additional milestone payments. On November 26, 2024 Roche moved to acquire Poseida outright for $9.00/share (~$1.0B) plus a non-tradeable CVR of up to $4.00/share (total up to ~$1.5B); the acquisition closed January 8, 2025 via Blue Giant Acquisition Corp., delisting Poseida from Nasdaq and folding the collaboration and its allogeneic CAR-T platform fully into Roche.

Key facts

Related deals — scored

DealYearValueOutcome
Roche Holding AG / Poseida Therapeutics (this deal)2022$6.1B
Roche Holding AG / Chugai Pharmaceutical Co. Ltd.2002$1.4B100
Roche Holding AG / Ventana Medical Systems Inc.2008$3.4B88
Roche Holding AG / Corange Ltd. (Boehringer Mannheim Group)1997$11.0B88
Roche Holding AG / Ventana Medical Systems Inc.2007$3.4B88
Roche Holding AG / Foundation Medicine, Inc.2015$1.1B87
Roche Holding AG / Foundation Medicine, Inc.2018$5.3B85

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