Pharma BD Deal Intelligence

Amgen Inc. / Horizon Therapeutics plc

2022 · Acquisition/Merger · $27.8B · Complete

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Top 5 largest deals of the 2020s

Ranks computed across 828 graded deals (Critic + Outcome Score both present).

The coverage arc

Jan 27, 2023 Horizon Therapeutics SC 14D-9/A Bullish

Horizon Therapeutics plc filed a Solicitation/Recommendation Statement on Schedule 14D-9 in connection with the Transaction Agreement dated December 11,…

Oct 06, 2023 BioPharma Dive Neutral

Amgen completes $28B Horizon buyout that was challenged by FTC. Amgen closed its $27.8 billion acquisition of Horizon Therapeutics, completing the largest…

Feb 04, 2025 Amgen Q4 & Full-Year 2024 Financial Results (Feb 2025) Neutral

Amgen FY2024 product sales: TEPEZZA $1,851M, KRYSTEXXA $1,185M, UPLIZNA $379M, TAVNEOS $283M (acquired Horizon portfolio total $3,698M), first full year under…

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Amgen acquired Horizon Therapeutics for approximately $27.8 billion ($116.50 per share in cash), gaining a portfolio of rare inflammatory disease medicines led by Tepezza (thyroid eye disease), Krystexxa (chronic refractory gout), and Uplizna (NMOSD). The deal overcame an FTC challenge resolved via consent order in September 2023.

Key facts

Related deals — scored

DealYearValueOutcome
Amgen Inc. / Horizon Therapeutics plc (this deal)2022$27.8B72
Amgen Inc. / Immunex Corporation2002$16.0B92
Amgen Inc. / Immunex Corporation2001$16.0B91
Amgen Inc. / Micromet Inc.2012$1.2B88
Amgen Inc. / Five Prime Therapeutics2021$1.9B78
Amgen Inc. / Otezla (from Celgene/BMS)2019$13.4B68
Amgen Inc. / BeiGene Ltd.2020$2.8B68

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