Pharma BD Deal Intelligence

Pfizer Inc. / ReViral Ltd.

2022 · Acquisition/Merger · $525M · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Apr 07, 2022 BioPharma Dive Bullish

Pfizer announced Thursday it has agreed to acquire UK biotech ReViral for as much as 525 million dollars including upfront and development milestones, picking…

Apr 07, 2022 Fierce Pharma Bullish

Pfizer is paying as much as 525 million dollars upfront and in milestones to acquire ReViral, a small UK-based biotech developing oral antivirals for…

Apr 08, 2022 BioSpace Bullish

Pfizer announced on Thursday that it has agreed to acquire ReViral, a clinical-stage biopharmaceutical company focused on respiratory syncytial virus…

Source summaries from our enrichment pipeline; follow links for originals.

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Pfizer agreed to acquire ReViral, a clinical-stage RSV antiviral biotech, for total consideration up to $525M including upfront and development milestones. Lead asset sisunatovir is an oral RSV fusion inhibitor with FDA Fast Track designation. Closed June 9, 2022. Note: existing DB record has data-quality issue (date 2002-07-15); this is the correct 2022 announcement. POST-CLOSE OUTCOME (reviewed 2026-06-07): The acquisition's clinical thesis failed. Pfizer discontinued sisunatovir in October 2024 for business reasons after 'ongoing challenges' in development, including a drug-drug interaction with antacids; there were no safety concerns. The adult RSV study NCT06079320 is listed as TERMINATED on ClinicalTrials.gov ('Study discontinued due to business reasons...no changes to sponsor's assessment of the risk-benefit profile'). Pediatric/infant studies were also halted. The second ReViral program (PF-07923567 / RV-299) had already been dropped in August 2023. Pfizer's RSV antiviral pipeline is now empty; its RSV strategy centers on the Abrysvo vaccine. Sources: ClinicalTrials.gov NCT06079320; FierceBiotech (2024-11-04); Endpoints News (2024-11-04).

Key facts

Related deals — scored

DealYearValueOutcome
Pfizer Inc. / ReViral Ltd. (this deal)2022$525M
Pfizer Inc. / BioNTech SE2020$748M100
Pfizer Inc. / FoldRx Pharmaceuticals201099
Pfizer Inc. / Medivation Inc.2016$14.0B86
Pfizer Inc. / Wyeth2009$68.0B86
Pfizer Inc. / Warner-Lambert Company2000$90.0B83
Pfizer Inc. / Arvinas, Inc.2021$2.4B77

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