Pharma BD Deal Intelligence

Pfizer Inc. / FoldRx Pharmaceuticals

2010 · Acquisition/Merger · Complete

CALLED IT — OFF BY 6

A roughly 400 million dollar bolt-on for an unapproved rare-disease drug became a 5.4 billion dollar per year Pfizer blockbuster franchise.

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The coverage arc

Sep 01, 2010 Fierce Biotech Bullish

Frames the buy as strategically sound: tafamidis, approaching an FDA filing as 'the first disease-modifying agent targeting the underlying cause of a human…

May 23, 2019 BioPharma Dive Neutral

BioPharma Dive flagged tafamidis's $225,000 list price and payer pushback as the central commercial risk to the launch — but acknowledged the FoldRx-acquired…

Jul 08, 2021 Axios Bullish

Pfizer's rare-heart-disease drug Vyndaqel — acquired through the 2010 FoldRx deal — is becoming a blockbuster with $1.3B in 2020 revenue and rapid growth…

Source summaries from our enrichment pipeline; follow links for originals.

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Pfizer agreed to acquire privately held FoldRx Pharmaceuticals to gain rare-disease platform anchored by tafamidis, a first-in-class TTR stabilizer. Deal value undisclosed.

Did it work? Outcome assessment

A roughly 400 million dollar bolt-on for an unapproved rare-disease drug became a 5.4 billion dollar per year Pfizer blockbuster franchise.

Strategic verdict
Achieved Stated Rationale

Key facts

Related deals — scored

DealYearValueOutcome
Pfizer Inc. / FoldRx Pharmaceuticals (this deal)201099
Pfizer Inc. / BioNTech SE2020$748M100
Pfizer Inc. / Medivation Inc.2016$14.0B86
Pfizer Inc. / Wyeth2009$68.0B86
Pfizer Inc. / Warner-Lambert Company2000$90.0B83
Pfizer Inc. / Arvinas, Inc.2021$2.4B77
Pfizer Inc. / Seagen Inc.2023$43.0B77

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