Pharma BD Deal Intelligence

Ipsen S.A. / GENFIT

2021 · Licensing/Option · $543M · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Dec 22, 2021 BioPharma Dive Neutral

Ipsen has licensed Genfit's elafibranor in a deal worth up to 480 million euros, betting the dual PPAR agonist can succeed in primary biliary cholangitis after…

Dec 23, 2021 BioSpace Bullish

Ipsen and Genfit have entered into a long-term strategic partnership granting Ipsen an exclusive worldwide license, excluding China, to elafibranor for primary…

Oct 23, 2024 www.ipsen.com Bullish

Ipsen 9M-2024 results: Iqirvo (elafibranor) in 2L PBC had its first full quarter of sales following U.S. approval and contributed to total-sales growth; Ipsen…

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Ipsen and Genfit entered a long-term strategic partnership (announced 22-Dec-2021) granting Ipsen an exclusive worldwide license, excluding Greater China, to develop and commercialize elafibranor for primary biliary cholangitis. Genfit received EUR 120M (~$136M) upfront (paid December 2021), an 8% equity investment by Ipsen, milestones up to EUR 360M (~$407M) and tiered double-digit royalties of up to 20%. The bet paid off: the Phase 3 ELATIVE trial met its primary endpoint, and the U.S. FDA granted accelerated approval to Iqirvo (elafibranor) for PBC on 10-Jun-2024 as the first-in-class oral PPAR agonist in the indication, followed by EU conditional approval (Sept 2024) and UK MHRA authorization. First U.S. commercial sale triggered a EUR 48.7M milestone (invoiced Jun 2024, collected Aug 2024), and Iqirvo began contributing to Ipsen sales in 2H-2024. The de-risked asset validates Ipsen's rare-disease specialty-care strategy.

Key facts

Related deals — scored

DealYearValueOutcome
Ipsen S.A. / GENFIT (this deal)2021$543M
Ipsen S.A. / Exelixis Inc.2016$855M80
Ipsen S.A. / Kartos Therapeutics, Inc.2026$1.8B68
Ipsen S.A. / Memo Therapeutics AG2026$797M66
Ipsen S.A. / Clementia Pharmaceuticals Inc.2019$1.3B
Ipsen S.A. / Marengo Therapeutics, Inc.2024$1.2B
Ipsen S.A. / Simcere Zaiming Pharmaceutical Co., Ltd.2025$1.1B

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