Pharma BD Deal Intelligence

Ipsen S.A. / Clementia Pharmaceuticals Inc.

2019 · Acquisition/Merger · $1.3B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Feb 25, 2019 Fierce Biotech Neutral

Jefferies said the '$1.0 billion upfront acquisition of Clementia should be well received,' but the piece flagged a failed midphase study raising efficacy…

Dec 05, 2019 Fierce Biotech Bearish

FDA placed palovarotene on partial clinical hold in pediatric FOP patients citing premature growth plate closure, an early setback to Ipsen's $1.04B Clementia…

Aug 17, 2023 Fierce Pharma Neutral

Four years and multiple regulatory setbacks after the $1.3B Clementia deal, palovarotene finally won FDA approval as Sohonos for FOP — though the MO indication…

Source summaries from our enrichment pipeline; follow links for originals.

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Ipsen agreed to acquire Clementia for up to $1.31B, comprising $1.04B upfront ($25/share) plus a CVR of $6/share (~$263M) tied to acceptance of palovarotene NDA filing. Adds rare bone disease assets including palovarotene for fibrodysplasia ossificans progressiva and multiple osteochondromas.

Did it work? Outcome assessment

Strategic verdict
Partially Achieved
Financial impact
Impaired/Written Down
Pipeline outcome
Mixed

Key facts

Related deals — scored

DealYearValueOutcome
Ipsen S.A. / Clementia Pharmaceuticals Inc. (this deal)2019$1.3B
Ipsen S.A. / Exelixis Inc.2016$855M80
Ipsen S.A. / Kartos Therapeutics, Inc.2026$1.8B68
Ipsen S.A. / Memo Therapeutics AG2026$797M66
Ipsen S.A. / Marengo Therapeutics, Inc.2024$1.2B
Ipsen S.A. / GENFIT2021$543M
Ipsen S.A. / Simcere Zaiming Pharmaceutical Co., Ltd.2025$1.1B

Compare all 7 side-by-side →

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