Pharma BD Deal Intelligence

Shire plc / Pervasis Therapeutics, Inc.

2012 · Asset Purchase · $200M · Complete

WRONG BY 65 POINTS

Vascugel was shelved in 2014 after unexpected trial complications, and Shire exited the whole Regenerative Medicine unit it belonged to within two years of the Pervasis deal.

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The coverage arc

Apr 10, 2012 MedCity News Bullish

Shire's Pervasis acquisition added Vascugel and an endothelial cell platform to its regenerative medicine division alongside Dermagraft, with deal value up to…

Apr 12, 2012 BioSpace Bullish

Shire to purchase substantially all Pervasis Therapeutics assets to fortify its regenerative medicine business, gaining the Vascugel platform to reestablish…

Jan 14, 2013 Shire (via Takeda archive) Neutral

Shire initiated two Phase 2 studies of SRM003/Vascugel in ESRD patients undergoing AV access creation for hemodialysis — confirming the asset advanced into…

Source summaries from our enrichment pipeline; follow links for originals.

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Shire acquired substantially all Pervasis Therapeutics assets for an undisclosed upfront plus milestone payments totaling up to ~$200M. Added Phase 2 Vascugel cell-based vascular access therapy to Shire's regenerative medicine business (alongside Dermagraft from 2011 Advanced BioHealing deal).

Did it work? Outcome assessment

Vascugel was shelved in 2014 after unexpected trial complications, and Shire exited the whole Regenerative Medicine unit it belonged to within two years of the Pervasis deal.

Strategic verdict
Failed to Achieve
Financial impact
Impaired/Written Down
Pipeline outcome
Assets Terminated

Key facts

Related deals — scored

DealYearValueOutcome
Shire plc / Pervasis Therapeutics, Inc. (this deal)2012$200M18
Shire plc / Dyax Corp.2016$5.9B89
Shire plc / New River Pharmaceuticals Inc.2007$2.6B88
Shire plc / Jerini AG2008$521M85
Shire plc / NPS Pharmaceuticals2015$5.2B78
Shire plc / Baxalta Inc.2016$32.0B77
Shire plc / ViroPharma Incorporated2013$4.2B58

Compare all 7 side-by-side →

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