Pharma BD Deal Intelligence

Shire plc / Baxalta Inc.

2016 · Acquisition/Merger · $32.0B · Complete

WRONG BY 41 POINTS
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Top 10 most underrated deals we track Top 25 largest deals of the 2010s

Ranks computed across 828 graded deals (Critic + Outcome Score both present).

The coverage arc

Jan 11, 2016 Boston Globe (Leerink Partners) Bullish

Leerink’s Jason Gerberry: deal is strategically important as it boosts rare disease drugs to about 65% of combined portfolio, cementing rare-disease leadership.

Aug 03, 2016 BioSpace (Leerink Partners) Bearish

Leerink’s Michael Schmidt: Shire discontinued Baxalta’s BAX-335 hemophilia B gene therapy post-acquisition, raising questions about pipeline value embedded in…

Apr 20, 2026 Market Realist Bearish

Shire shares fell 9% on announcement. Wall Street questioned whether Shire paid too much given fierce hemophilia competition from Biogen, Roche, and BioMarin.

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Shire acquired Baxalta for $32B for rare disease and hematology.

Key facts

Related deals — scored

DealYearValueOutcome
Shire plc / Baxalta Inc. (this deal)2016$32.0B77
Shire plc / Dyax Corp.2016$5.9B89
Shire plc / New River Pharmaceuticals Inc.2007$2.6B88
Shire plc / Jerini AG2008$521M85
Shire plc / NPS Pharmaceuticals2015$5.2B78
Shire plc / ViroPharma Incorporated2013$4.2B58
Shire plc / Movetis NV2010$565M37

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