Pharma BD Deal Intelligence

Shire plc / New River Pharmaceuticals Inc.

2007 · Acquisition/Merger · $2.6B · Complete

CALLED IT — OFF BY 0

Vyvanse turned a $2.6B bolt-on into one of the most successful ADHD franchises in pharma history, generating $2B+/year at peak — until a marketing-fraud settlement and 2023 generic cliff closed the chapter.

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The coverage arc

Feb 20, 2007 SEC / Shire-New River joint release Neutral

Shire agreed to acquire New River for $64/share (~$2.6B all cash) to gain full control of Vyvanse, funded by $2.3B in new debt and $800M of equity.

Feb 22, 2007 Chemical & Engineering News Bullish

C&EN noted Vyvanse's prodrug design lowered abuse liability and positioned Shire to defend ADHD share once Adderall XR went generic.

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$64/share, ~$2.6B all-cash. Vyvanse (lisdexamfetamine) ADHD prodrug. Source: SEC, Shire/NRP press release, PharmaTimes.

Did it work? Outcome assessment

Vyvanse turned a $2.6B bolt-on into one of the most successful ADHD franchises in pharma history, generating $2B+/year at peak — until a marketing-fraud settlement and 2023 generic cliff closed the chapter.

Strategic verdict
Achieved Stated Rationale

Key facts

Related deals — scored

DealYearValueOutcome
Shire plc / New River Pharmaceuticals Inc. (this deal)2007$2.6B88
Shire plc / Dyax Corp.2016$5.9B89
Shire plc / Jerini AG2008$521M85
Shire plc / NPS Pharmaceuticals2015$5.2B78
Shire plc / Baxalta Inc.2016$32.0B77
Shire plc / ViroPharma Incorporated2013$4.2B58
Shire plc / Movetis NV2010$565M37

Compare all 7 side-by-side →

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