Pharma BD Deal Intelligence

Sanofi SA / Lexicon Pharmaceuticals Inc.

2015 · Licensing/Option · $1.7B · Terminated

WRONG BY 31 POINTS
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The coverage arc

Nov 06, 2015 PR Newswire Bullish

Under the terms of the agreement, Lexicon will receive an upfront payment of $300 million and is eligible to receive development, regulatory and sales…

Jul 29, 2019 Genetic Engineering & Biotechnology News Neutral

Lexicon fires back after Sanofi ends up-to-$1.7B diabetes collaboration. Total deal potential was $1.7 billion including $300 million upfront and $1.4 billion…

Aug 04, 2025 FDANews Neutral

Sanofi partners with Lexicon Pharmaceuticals to develop sotagliflozin, with Lexicon receiving a $300 million upfront payment and eligibility for up to…

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Sanofi licensed sotagliflozin, a dual SGLT1/SGLT2 inhibitor, from Lexicon for global development and commercialization in diabetes and cardiovascular disease. Lexicon received $300M upfront, $100M equity, with up to $2.42B in milestones. The deal was terminated by Sanofi in 2019 following regulatory setbacks. Lexicon later independently obtained approval for Inpefa (sotagliflozin) for heart failure in 2023.

Key facts

Related deals — scored

DealYearValueOutcome
Sanofi SA / Lexicon Pharmaceuticals Inc. (this deal)2015$1.7B44
Sanofi SA / Regeneron Pharmaceuticals, Inc.2007$1.0B97
Sanofi SA / Synthelabo S.A.1998$11.0B84
Sanofi SA / Genzyme Corporation2011$20.1B84
Sanofi SA / Amunix Pharmaceuticals Inc.2021$1.2B76
Sanofi SA / Genzyme Corporation2010$18.5B75
Sanofi SA / Translate Bio Inc.2018$805M73

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