Pharma BD Deal Intelligence

Sanofi SA / Lexicon Pharmaceuticals Inc.

2015 · Licensing/Option · $1.7B · Terminated

Announcement Sentiment
75
Strongly positive
Outcome Score
44
Underwhelmed — fell short of the thesis.

Sanofi licensed sotagliflozin, a dual SGLT1/SGLT2 inhibitor, from Lexicon for global development and commercialization in diabetes and cardiovascular disease. Lexicon received $300M upfront, $100M equity, with up to $2.42B in milestones. The deal was terminated by Sanofi in 2019 following regulatory setbacks. Lexicon later independently obtained approval for Inpefa (sotagliflozin) for heart failure in 2023.

Key facts

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