Pharma BD Deal Intelligence

Sanofi SA / Earendil Labs, Inc.

2025 · Licensing/Option · $1.8B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Apr 17, 2025 BioPharma Dive Bullish

French drugmaker Sanofi agreed to pay $125 million to startup Earendil Labs for two drug candidates designed to treat autoimmune and inflammatory bowel…

Apr 17, 2025 Fierce Biotech Bullish

Sanofi pens $1.8B research deal for 2 bispecific antibodies aimed at autoimmune, immunology. The deal sees Sanofi handing over $125 million upfront with a…

Jan 05, 2026 PR Newswire Bullish

Jan 5, 2026: Earendil and Sanofi announced a SEPARATE, expanded strategic collaboration applying Earendil's AI discovery platform to multiple…

Source summaries from our enrichment pipeline; follow links for originals.

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Sanofi obtained exclusive worldwide rights to two AI-engineered bispecific antibodies (HXN-1002 targeting α4β7/TL1A and HXN-1003 targeting TL1A/IL23) for autoimmune and IBD indications. Earendil received $125M upfront and is eligible for up to $1.72B in milestones plus tiered royalties. Follow-on validation: in January 2026 Sanofi and Earendil signed a separate, broader strategic collaboration (up to $160M upfront/near-term, up to $2.56B total) applying Earendil's AI discovery platform to additional autoimmune/inflammatory programs, reinforcing the platform thesis behind this initial HXN-1002/HXN-1003 license.

Key facts

Related deals — scored

DealYearValueOutcome
Sanofi SA / Earendil Labs, Inc. (this deal)2025$1.8B
Sanofi SA / Regeneron Pharmaceuticals, Inc.2007$1.0B97
Sanofi SA / Synthelabo S.A.1998$11.0B84
Sanofi SA / Genzyme Corporation2011$20.1B84
Sanofi SA / Amunix Pharmaceuticals Inc.2021$1.2B76
Sanofi SA / Genzyme Corporation2010$18.5B75
Sanofi SA / Translate Bio Inc.2018$805M73

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