Pharma BD Deal Intelligence

Gilead Sciences Inc. / CV Therapeutics Inc.

2009 · Acquisition/Merger · $1.4B · Complete

Gilead's $1.4B acquisition of CV Therapeutics landed as a partial win, built around Ranexa. The deal delivered solid financial return but weaker strategic fit, leaving the "Partially Achieved" verdict rather than a clean success.

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Gilead / CV Therapeutics: Partially Achieved (Score: 64/100)

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Gilead acquired CV Therapeutics for $1.4B for Ranexa and Lexiscan.

Did it work? Outcome assessment

Gilead / CV Therapeutics: Partially Achieved (Score: 64/100)

Strategic verdict
Partially Achieved

Key facts

Disease & market context

Chronic Stable Angina

6M US cases/yr · $2.0B US Angina Therapeutics Market (2009) · 15.4M Americans with CHD

Disease Overview

Chronic stable angina affects over 6 million Americans. Ranexa (ranolazine) was the first new angina drug in over a decade (2006), working via late sodium current inhibition. Gilead's $1.4B acquisition of CV Therapeutics added cardiovascular assets.

Post-Deal Context

Ranexa achieved ~$600M peak US sales but became non-core as Gilead pivoted to HCV (Sovaldi/Harvoni) and HIV. Ranexa went generic after 2019 patent expiry. The deal is viewed as strategically secondary to the Pharmasset acquisition.

Deal timeline

Related deals — scored

DealYearValueOutcome
Gilead Sciences Inc. / CV Therapeutics Inc. (this deal)2009$1.4B62
Gilead Sciences Inc. / Pharmasset Inc.2011$11.2B98
Gilead Sciences Inc. / Triangle Pharmaceuticals Inc.2002$464M96
Gilead Sciences Inc. / CymaBay Therapeutics2024$4.4B76
Gilead Sciences Inc. / Nurix Therapeutics Inc.2019$2.3B69
Gilead Sciences Inc. / Immunomedics Inc.2020$21.0B68
Gilead Sciences Inc. / Kite Pharma, Inc.2017$11.9B67

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