Pharma BD Deal Intelligence

Gilead Sciences Inc. / Calistoga Pharmaceuticals, Inc.

2011 · Acquisition/Merger · $600M · Complete

WRONG BY 29 POINTS
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The coverage arc

Feb 22, 2011 Fierce Biotech (John Carroll) Bullish

Frames the buyout as a strategic expansion into oncology and inflammation, highlighting Calistoga's first-mover clinical validation of PI3K-delta inhibition…

Feb 23, 2011 PharmaTimes Bullish

Leerink Swann analyst Joshua Schimmer called CAL-101 'one of the more promising emerging oncology assets.'

May 19, 2022 BioSpace Bearish

Gilead voluntarily withdrew Zydelig's FL and SLL indications in May 2022 after failing to complete required post-marketing confirmatory studies, leaving CLL…

Source summaries from our enrichment pipeline; follow links for originals.

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Gilead acquired Calistoga for $375M upfront plus up to $225M in milestones. Lead asset CAL-101 (idelalisib) was an oral PI3K-delta inhibitor in clinical development for B-cell malignancies; later approved as Zydelig in 2014.

Did it work? Outcome assessment

Strategic verdict
Partially Achieved
Financial impact
Dilutive
Pipeline outcome
Mixed

Key facts

Related deals — scored

DealYearValueOutcome
Gilead Sciences Inc. / Calistoga Pharmaceuticals, Inc. (this deal)2011$600M35
Gilead Sciences Inc. / Pharmasset Inc.2011$11.2B98
Gilead Sciences Inc. / Triangle Pharmaceuticals Inc.2002$464M96
Gilead Sciences Inc. / CymaBay Therapeutics2024$4.4B76
Gilead Sciences Inc. / Nurix Therapeutics Inc.2019$2.3B69
Gilead Sciences Inc. / Immunomedics Inc.2020$21.0B68
Gilead Sciences Inc. / Kite Pharma, Inc.2017$11.9B67

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