Pharma BD Deal Intelligence

Roche Holding AG / Spark Therapeutics Inc.

2019 · Acquisition/Merger · $4.3B · Complete

CALLED IT — OFF BY 13
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Ranks computed across 828 graded deals (Critic + Outcome Score both present).

The coverage arc

Mar 24, 2004 Wikipedia Neutral

Roche acquired Spark Therapeutics for $4.3B for gene therapy including Luxturna.

Feb 03, 2023 BioPharma Dive Bearish

Feb 2023: Roche took ~CHF 740M impairment on Spark assets (Luxturna + hemophilia A/B + Pompe), part of ~$3B in 2022 gene-therapy/oncology write-downs, citing…

Apr 03, 2025 Philadelphia Inquirer Bearish

April 3, 2025: Roche-owned Spark Therapeutics laying off 337 of ~650 employees (more than half its workforce) in three waves (May, July, December 2025);…

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Roche acquired Spark Therapeutics for approximately $4.3 billion ($114.50 per share) in an all-cash tender offer, gaining Luxturna (voretigene neparvovec), the first FDA-approved gene therapy for a genetic disease, along with a hemophilia gene therapy pipeline.

Key facts

Related deals — scored

DealYearValueOutcome
Roche Holding AG / Spark Therapeutics Inc. (this deal)2019$4.3B27
Roche Holding AG / Chugai Pharmaceutical Co. Ltd.2002$1.4B100
Roche Holding AG / Ventana Medical Systems Inc.2008$3.4B88
Roche Holding AG / Corange Ltd. (Boehringer Mannheim Group)1997$11.0B88
Roche Holding AG / Ventana Medical Systems Inc.2007$3.4B88
Roche Holding AG / Foundation Medicine, Inc.2015$1.1B87
Roche Holding AG / Foundation Medicine, Inc.2018$5.3B85

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