Pharma BD Deal Intelligence

Roche Holding AG / Bicycle Therapeutics plc

2020 · Co-Development · $1.7B · Terminated

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Feb 28, 2020 BioPharma Dive Bullish

U.K. biotech Bicycle Therapeutics has signed a deal with Genentech to develop immuno-oncology therapies based on its bicyclic peptide platform. Bicycle will…

Feb 28, 2020 Fierce Biotech Bullish

Roche's Genentech has tapped Bicycle Therapeutics for a 1.7 billion dollar immuno-oncology collaboration, marking the highest-profile validation yet for…

Aug 03, 2023 Endpoints News Neutral

Bicycle Therapeutics provided a strategic update on its Genentech collaboration on its second-quarter 2023 earnings call, noting continued advancement of…

Source summaries from our enrichment pipeline; follow links for originals.

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Genentech (Roche) and Bicycle Therapeutics entered an exclusive strategic collaboration to discover, develop and commercialize Bicycle-based immuno-oncology therapies. Bicycle received $30M upfront with eligibility for up to ~$1.7B in milestones across multiple programs plus tiered royalties. Genentech selected initial two targets with options on additional targets via $10M expansion fees.

Key facts

Related deals — scored

DealYearValueOutcome
Roche Holding AG / Bicycle Therapeutics plc (this deal)2020$1.7B
Roche Holding AG / Chugai Pharmaceutical Co. Ltd.2002$1.4B100
Roche Holding AG / Ventana Medical Systems Inc.2008$3.4B88
Roche Holding AG / Corange Ltd. (Boehringer Mannheim Group)1997$11.0B88
Roche Holding AG / Ventana Medical Systems Inc.2007$3.4B88
Roche Holding AG / Foundation Medicine, Inc.2015$1.1B87
Roche Holding AG / Foundation Medicine, Inc.2018$5.3B85

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