Pharma BD Deal Intelligence

Remix Therapeutics, Inc. / Passage Bio, Inc.

2026 · Reverse Merger · $226M · Pending

A no-fanfare all-stock reverse merger that put Remix Therapeutics in the public markets via Passage Bio's shell, with Remix holders taking ~93% and Passage investors left with a thin 7% stake plus a contingent value right on the legacy gene-therapy pipeline. The deal funds Remix's oral MYB degrader REM-422 into 2028, though Passage shareholders got little more than an exit ramp.

CALLED IT — OFF BY 11

Remix takes Passage Bio's Nasdaq listing to advance oral mRNA degrader

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On June 24, 2026, Remix Therapeutics announced it will go public via an all-stock reverse merger with Passage Bio (Nasdaq: PASG), a gene-therapy company co-founded by Jim Wilson. Concurrent with the deal, Remix secured commitments for a $100 million private financing closing just before the merger. Remix investors will own ~93% of the combined company and Passage holders ~7% plus a contingent value right tied to Passage's licensed pediatric gene-therapy assets. The combined company will trade as Remix under ticker RMTX and advance REM-422, an oral MYB mRNA degrader in a Phase 1/2 study in adenoid cystic carcinoma (ACC) and a Phase 1 study in AML/high-risk MDS. Cash is expected to fund operations into 2028; close expected Q4 2026.

Key facts

Disease & market context

Adenoid Cystic Carcinoma & Myeloid Malignancies (mRNA Degrader)

Disease Overview

Remix Therapeutics' lead candidate REM-422 is an oral small-molecule mRNA degrader designed to reduce MYB oncogene expression. It is in a Phase 1/2 study in adenoid cystic carcinoma (ACC) and a Phase 1 study in acute myeloid leukemia and high-risk myelodysplastic syndromes. Remix reaches Nasdaq via reverse merger with Passage Bio plus a $100M financing; the combined company (ticker RMTX) expects cash to fund operations into 2028. Deal terms are an all-stock reverse merger (value undisclosed).

Deal timeline

Related deals — scored

DealYearValueOutcome
Remix Therapeutics, Inc. / Passage Bio, Inc. (this deal)2026$226M61
AstraZeneca PLC / Daiichi Sankyo Company, Limited2019$6.9B100
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Astellas Pharma Inc. / Seagen Inc.2009$4.5B95
Bristol-Myers Squibb Company / Medarex Inc.2009$2.4B92
Servier / Agios Pharmaceuticals (oncology)2020$2.0B91
Servier Pharmaceuticals LLC / Agios Pharmaceuticals Inc.2020$2.0B91

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