Pharma BD Deal Intelligence

Pfizer Inc. / Metsera, Inc.

2025 · Acquisition/Merger · $10.0B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Nov 07, 2025 BioPharma Dive Bullish

Pfizer wins the bidding war for Metsera with a $10 billion offer. Metsera stated Novo Nordisk's proposal presented 'unacceptably high legal and regulatory…

Feb 03, 2026 BioSpace Bullish

Pfizer's First Weight-Loss Data After Metsera Buy 'Look Competitive'. BMO Capital Markets assessed that Pfizer's weight-loss results look competitive with…

May 01, 2026 SEC EDGAR (Pfizer 10-Q FY2026 Q1) Neutral

Pfizer 10-Q for quarter ended March 29, 2026 reflects the Metsera acquisition: ~$7B upfront cash consideration plus contingent value rights; guided to reduce…

Source summaries from our enrichment pipeline; follow links for originals.

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Pfizer agreed (Sept 22, 2025) to acquire Metsera initially at $47.50/share cash plus CVR up to $22.50/share (~$10B total). After Novo Nordisk launched a rival ~$8.5B bid in October, Pfizer raised its offer; the amended merger (Nov 7, 2025) set $65.60/share cash upfront (~$7.0B enterprise value) plus a CVR of up to $20.65/share ($4.60 + $6.40 + $9.65 across three clinical/regulatory milestones), keeping the up-to total near $10B. Metsera cited FTC antitrust risk in Novos bid; Pfizer prevailed and closed Nov 13, 2025. The deal gives Pfizer Metseras next-generation obesity portfolio led by ultra-long-acting injectable GLP-1 MET-097i and amylin analog MET-233i.

Key facts

Related deals — scored

DealYearValueOutcome
Pfizer Inc. / Metsera, Inc. (this deal)2025$10.0B
Pfizer Inc. / BioNTech SE2020$748M100
Pfizer Inc. / FoldRx Pharmaceuticals201099
Pfizer Inc. / Medivation Inc.2016$14.0B86
Pfizer Inc. / Wyeth2009$68.0B86
Pfizer Inc. / Warner-Lambert Company2000$90.0B83
Pfizer Inc. / Arvinas, Inc.2021$2.4B77

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