Pharma BD Deal Intelligence

Pfizer Inc. / Coley Pharmaceutical Group Inc.

2007 · Acquisition/Merger · $164M · Complete

WRONG BY 57 POINTS

Pfizer bought a TLR9/vaccine-adjuvant platform whose lead asset had already failed in Phase 3, then shuttered the whole unit three years later with no product ever reaching market.

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The coverage arc

Aug 15, 2006 PubMed (Adis R&D Profile) Neutral

CpG 7909/PF-3512676 was being developed across NSCLC, renal cell carcinoma, lymphoma, melanoma, and as adjuvant for hepatitis B and influenza vaccines—broad…

Nov 16, 2007 FierceBiotech Neutral

Pfizer buys Coley for $164M, gaining its Toll-like receptor immunomodulator platform; coverage notes the buyout follows Pfizer's earlier discontinuation of the…

Nov 19, 2007 PharmaTimes Neutral

Pfizer paid a sizeable premium ($8 vs ~$3 prior close) just months after halting the Phase 3 NSCLC trial for PF-3512676—signaling a platform bet rather than a…

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Pfizer agreed to acquire Coley Pharmaceutical Group for $8.00 per share (approximately $164 million) to add TLR-9 agonist immunomodulators to its pipeline. The tender offer expired December 28, 2007.

Did it work? Outcome assessment

Pfizer bought a TLR9/vaccine-adjuvant platform whose lead asset had already failed in Phase 3, then shuttered the whole unit three years later with no product ever reaching market.

Strategic verdict
Failed to Achieve

Key facts

Related deals — scored

DealYearValueOutcome
Pfizer Inc. / Coley Pharmaceutical Group Inc. (this deal)2007$164M13
Pfizer Inc. / BioNTech SE2020$748M100
Pfizer Inc. / FoldRx Pharmaceuticals201099
Pfizer Inc. / Medivation Inc.2016$14.0B86
Pfizer Inc. / Wyeth2009$68.0B86
Pfizer Inc. / Warner-Lambert Company2000$90.0B83
Pfizer Inc. / Arvinas, Inc.2021$2.4B77

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