Pharma BD Deal Intelligence

Otsuka Pharmaceutical Co. Ltd. / Astex Pharmaceuticals

2013 · Acquisition/Merger · $886M · Complete

WRONG BY 43 POINTS
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Ranks computed across 828 graded deals (Critic + Outcome Score both present).

The coverage arc

Oct 02, 2013 Fierce Biotech (Sarissa Capital open letter) Bearish

Sarissa Capital, holder of approximately 5% of Astex shares, said the announced merger with Otsuka significantly undervalues Astex and that it did not intend…

Jul 30, 2018 Genetic Engineering & Biotechnology News Bearish

ASTRAL-1 missed CR and OS endpoints in treatment-naive unfit AML — a setback for Otsuka's $866M Astex deal, though Astex's Mohammad Azab pointed to 'very…

Oct 14, 2020 FierceBiotech Bearish

Guadecitabine has now failed three late-phase trials, leaving Otsuka 'facing the prospect of being unable to generate a return on the lead clinical program…

Source summaries from our enrichment pipeline; follow links for originals.

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Otsuka to acquire Astex at $8.50/share cash (~$886M); brings SGI-110 hypomethylating agent and Pyramid fragment-based platform plus oncology/CNS pipeline.

Did it work? Outcome assessment

Strategic verdict
Partially Achieved
Financial impact
Neutral
Pipeline outcome
Mixed

Key facts

Related deals — scored

DealYearValueOutcome
Otsuka Pharmaceutical Co. Ltd. / Astex Pharmaceuticals (this deal)2013$886M79
Amgen Inc. / Micromet Inc.2012$1.2B88
Servier / Shire plc (Oncology Business)2018$2.4B88
AstraZeneca PLC / Alexion Pharmaceuticals Inc.2020$39.0B86
Swedish Orphan Biovitrum AB / Biovitrum2001$493M84
AbbVie Inc. / Pharmacyclics Inc.2015$21.0B79
Shire plc / Baxalta Inc.2016$32.0B77

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