Pharma BD Deal Intelligence

LEO Pharma A/S / Replay Holdings LLC

2026 · Acquisition/Merger · $50M · Pending

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Apr 30, 2026 BioSpace Bullish

The acquisition adds a high-payload herpes simplex virus (HSV) gene therapy targeting genetic skin diseases to LEO Pharma's pipeline. HSV's natural tropism for…

Apr 30, 2026 Scrip (Citeline) Bullish

LEO Pharma is making its first significant gene therapy bet through the $50 million acquisition of Replay, picking up a preclinical HSV-vectored topical gene…

May 14, 2026 Latham & Watkins Neutral

Latham & Watkins, deal counsel to LEO Pharma, states LEO 'entered into a definitive agreement to acquire' Replay's gene therapy platform — confirming the…

Source summaries from our enrichment pipeline; follow links for originals.

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LEO Pharma signed a definitive agreement to acquire Replay for $50M upfront plus undisclosed milestones and tiered single-digit royalties, adding a preclinical HSV gene therapy platform targeting dystrophic epidermolysis bullosa to LEO's rare dermatology pipeline.

Key facts

Related deals — scored

DealYearValueOutcome
LEO Pharma A/S / Replay Holdings LLC (this deal)2026$50M
LEO Pharma A/S / AstraZeneca PLC2016$1.1B80
Ciba-Geigy AG / Sandoz AG1996$36.3B98
Sanofi SA / Regeneron Pharmaceuticals, Inc.2007$1.0B97
AbbVie Inc. / Boehringer Ingelheim GmbH2016$2.2B95
Amgen Inc. / Immunex Corporation2001$16.0B91
Takeda Pharmaceutical Company Ltd. / Nimbus Lakshmi2022$6.0B82

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