Pharma BD Deal Intelligence

Janssen Biotech, Inc. (Johnson & Johnson) / MacroGenics, Inc.

2016 · Co-Development · $740M · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

May 18, 2016 GEN - Genetic Engineering & Biotechnology News Bullish

GEN detailed the deal terms: $75M upfront, up to $665M in milestones, double-digit royalties, plus a US/Canada co-promote and profit-sharing option — Janssen's…

Jun 28, 2016 MacroGenics IR Bullish

MacroGenics confirmed deal closing on June 28, 2016, triggering the $75M upfront — validating company narrative that DART platform partnering remained a viable…

Sep 05, 2017 BioPharma Dive Bearish

BioPharma Dive (covering the related MGD011 termination): the decision 'raises questions about the promise of MacroGenics' DART platform' as competitive…

Source summaries from our enrichment pipeline; follow links for originals.

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MacroGenics granted Janssen a global, exclusive license to MGD015, a preclinical CD3 x tumor-target bispecific DART molecule. MacroGenics received $75M upfront plus up to $665M in clinical, regulatory, and commercialization milestones (~$740M total) plus tiered royalties on global sales. Second deal between the parties (followed 2014 MGD011 deal).

Key facts

Related deals — scored

DealYearValueOutcome
Janssen Biotech, Inc. (Johnson & Johnson) / MacroGenics, Inc. (this deal)2016$740M
Amgen Inc. / Micromet Inc.2012$1.2B88
Servier / Shire plc (Oncology Business)2018$2.4B88
AstraZeneca PLC / Alexion Pharmaceuticals Inc.2020$39.0B86
Swedish Orphan Biovitrum AB / Biovitrum2001$493M84
Otsuka Pharmaceutical Co. Ltd. / Astex Pharmaceuticals2013$886M79
AbbVie Inc. / Pharmacyclics Inc.2015$21.0B79

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