Pharma BD Deal Intelligence

GlaxoSmithKline plc / Adaptimmune Therapeutics plc

2014 · Co-Development · $350M · Terminated

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Jun 01, 2014 Pharmaceutical Technology Neutral

Adaptimmune and GSK entered a strategic collaboration for up to five programs including the lead NY-ESO TCR program, with cash payments of approximately…

Feb 02, 2016 FierceBiotech Bullish

GSK upsizes its bet on Adaptimmune, accelerating NY-ESO-1 SPEAR T-cell therapy toward registration trials in synovial sarcoma — raising potential program value…

Sep 07, 2017 GSK Newsroom Neutral

GSK exercised its exclusive option for the NY-ESO SPEAR T-cell program ahead of schedule, paying Adaptimmune ~£48M; program later returned to Adaptimmune in…

Source summaries from our enrichment pipeline; follow links for originals.

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GSK and Adaptimmune signed a strategic collaboration covering up to five engineered TCR cell-therapy programs led by NY-ESO-1, with potential payments up to $350M over seven years. The deal validated Adaptimmune's SPEAR platform and was the foundation for letetresgene autoleucel; ultimately wound down by GSK in 2024.

Key facts

Related deals — scored

DealYearValueOutcome
GlaxoSmithKline plc / Adaptimmune Therapeutics plc (this deal)2014$350M
GlaxoSmithKline plc / Theravance, Inc.2012$213M82
GlaxoSmithKline plc / Tesaro Inc.2018$5.1B79
GlaxoSmithKline plc / Pfizer Inc. (Consumer Healthcare Division)2018$12.7B76
GlaxoSmithKline plc / Novartis Consumer Healthcare JV2018$13.0B74
GlaxoSmithKline plc / ID Biomedical Corporation2005$1.4B64
GlaxoSmithKline plc / Vir Biotechnology Inc.2020$595M51

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