Pharma BD Deal Intelligence

Genmab A/S / Bolt Biotherapeutics, Inc.

2021 · Co-Development · $880M · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Jan 12, 2021 American Cancer Society Cancer Facts & Figures 2021 Neutral

In 2021 the American Cancer Society projected 1.9 million new cancer cases and 608,570 cancer deaths in the United States. Breast cancer accounted for an…

Jun 22, 2021 AACR 2021 — BDC-1001 Phase 1 abstract Bullish

BDC-1001, a HER2-targeted ISAC consisting of a trastuzumab biosimilar covalently linked to a proprietary TLR7/8 agonist, was administered in dose escalation to…

Jan 04, 2024 Fierce Biotech Bearish

Bolt Biotherapeutics is laying off 50% of its workforce after the company's research collaboration with Genmab failed to advance any candidates beyond…

Source summaries from our enrichment pipeline; follow links for originals.

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Genmab and Bolt entered an oncology R&D collaboration combining Genmab's antibody and bispecific platforms with Bolt's Boltbody ISAC technology. Bolt received $10M upfront plus a $15M equity investment and is eligible for up to $285M per program for up to three Genmab-developed candidates plus tiered royalties.

Key facts

Related deals — scored

DealYearValueOutcome
Genmab A/S / Bolt Biotherapeutics, Inc. (this deal)2021$880M
Genmab A/S / ProfoundBio Inc.2024$1.8B64
Genmab A/S / Merus N.V.2025$8.0B
AstraZeneca PLC / Daiichi Sankyo Company, Limited2019$6.9B100
Novartis AG / Endocyte, Inc.2018$2.1B96
Astellas Pharma Inc. / Seagen Inc.2009$4.5B95
Bristol-Myers Squibb Company / Medarex Inc.2009$2.4B92

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