Pharma BD Deal Intelligence

Eli Lilly and Company / Merus N.V.

2021 · Licensing/Option · $1.7B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Jan 12, 2021 American Cancer Society Neutral

In 2021, the American Cancer Society projects 1,898,160 new cancer cases and 608,570 cancer deaths in the United States. Solid tumors account for approximately…

Jan 19, 2021 Reuters Bullish

Eli Lilly has agreed to pay Dutch biotech Merus up to $1.66 billion in a research collaboration to develop CD3 bispecific antibody T-cell engagers. Lilly is…

May 26, 2022 IQVIA Institute Neutral

Global spending on oncology medicines reached $185 billion in 2021, an 11% increase from 2020, and is forecast to reach $300 billion by 2026 driven by…

Source summaries from our enrichment pipeline; follow links for originals.

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Loxo Oncology at Lilly and Merus entered an exclusive research collaboration and license agreement for up to three CD3-redirecting bispecific antibodies leveraging Merus' Biclonics platform. Merus received $40M upfront and a $20M equity investment, plus eligibility for up to $540M in development/commercialization milestones per product (~$1.6B total) and tiered royalties.

Key facts

Related deals — scored

DealYearValueOutcome
Eli Lilly and Company / Merus N.V. (this deal)2021$1.7B
Eli Lilly and Company / Boehringer Ingelheim GmbH2011$444M89
Eli Lilly and Company / Loxo Oncology, Inc.2019$8.0B88
Eli Lilly and Company / Applied Molecular Evolution Inc.2003$400M88
Eli Lilly and Company / ICOS Corporation2006$2.3B87
Eli Lilly and Company / Novartis Animal Health2014$5.4B70
Eli Lilly and Company / Incyte Corporation2009$755M69

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