Pharma BD Deal Intelligence

Eli Lilly and Company / Hanmi Pharmaceutical Co., Ltd. (HM71224 program)

2015 · Licensing/Option · $690M · Terminated

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Mar 19, 2015 BioSpace Neutral

Lilly and Hanmi forge $690 million autoimmune pact; Lilly cited significant unmet medical need in many prevalent autoimmune diseases where individual patient…

Feb 20, 2018 BioPharma Dive Bearish

Lilly characterized the interim Phase 2 result bluntly: 'the difference between the placebo and active treatment arms of the study was not sufficient enough to…

Feb 21, 2018 Pharmaphorum Bearish

Coverage noted Lilly's decision left HM71224 chasing alternative indications (lupus, lupus nephritis, Sjogren's) in a category where AbbVie/Janssen's Imbruvica…

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Lilly and Hanmi entered an exclusive worldwide (excluding China, Hong Kong, Korea) license and collaboration for HM71224, an oral BTK inhibitor for autoimmune diseases. Hanmi received $50M upfront with up to $640M in development, regulatory, and sales milestones plus tiered double-digit royalties. Lilly terminated the deal in 2019 after Phase 2 RA trial failed.

Key facts

Related deals — scored

DealYearValueOutcome
Eli Lilly and Company / Hanmi Pharmaceutical Co., Ltd. (HM71224 program) (this deal)2015$690M
Eli Lilly and Company / Boehringer Ingelheim GmbH2011$444M89
Eli Lilly and Company / Loxo Oncology, Inc.2019$8.0B88
Eli Lilly and Company / Applied Molecular Evolution Inc.2003$400M88
Eli Lilly and Company / ICOS Corporation2006$2.3B87
Eli Lilly and Company / Novartis Animal Health2014$5.4B70
Eli Lilly and Company / Incyte Corporation2009$755M69

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