Pharma BD Deal Intelligence

Eli Lilly and Company / Centrexion Therapeutics Corporation

2019 · Licensing/Option · $575M · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Jan 17, 2018 Healio Rheumatology Neutral

Reference for batch-sheet asset CNTX-4975 (Centrexion's lead, FDA Fast Track, Phase 3 VICTORY-3 in knee OA pain)—not part of the 2019 Lilly license per primary…

May 23, 2019 Genetic Engineering & Biotechnology News Bullish

Total deal potential ~$997M including sales milestones; Centrexion CEO Jeffrey Kindler positioned the deal as validation of Centrexion's ability to 'identify…

May 23, 2019 Pharmaceutical Business Review Neutral

Reinforced that Lilly's 2019 Centrexion license was for CNTX-0290 (not CNTX-4975); deal extends Lilly's pain portfolio after tanezumab regulatory setbacks and…

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Lilly licensed exclusive worldwide rights to CNTX-0290, a Phase 1 small molecule SSTR4 agonist for chronic pain, from Centrexion Therapeutics. Upfront $47.5M, up to $575M in development/regulatory milestones, up to $375M in sales milestones, plus tiered high-single to low-double digit royalties. Optional U.S. co-promotion election.

Key facts

Related deals — scored

DealYearValueOutcome
Eli Lilly and Company / Centrexion Therapeutics Corporation (this deal)2019$575M
Eli Lilly and Company / Boehringer Ingelheim GmbH2011$444M89
Eli Lilly and Company / Loxo Oncology, Inc.2019$8.0B88
Eli Lilly and Company / Applied Molecular Evolution Inc.2003$400M88
Eli Lilly and Company / ICOS Corporation2006$2.3B87
Eli Lilly and Company / Novartis Animal Health2014$5.4B70
Eli Lilly and Company / Incyte Corporation2009$755M69

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