Pharma BD Deal Intelligence

Eisai Co., Ltd. / SEED Therapeutics Inc.

2024 · Licensing/Option · $1.5B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Aug 06, 2024 BioSpace Bullish

SEED Therapeutics scored a $1.5 billion biobucks collaboration with Eisai, marking the biotech's second major pharma partnership following a 2022 deal with Eli…

Aug 06, 2024 Reuters Neutral

Japan's Eisai said on Tuesday it has entered a strategic research collaboration with U.S. biotech SEED Therapeutics to discover novel molecular glue degraders…

Aug 07, 2024 Fierce Pharma Bullish

Eisai is reaching beyond its Leqembi Alzheimer's franchise with a $1.5 billion molecular glue collaboration with SEED Therapeutics, including a Series…

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SEED Therapeutics entered strategic research collaboration with Eisai to discover molecular glue degraders for undisclosed neurodegeneration and oncology targets. SEED eligible for upfront plus preclinical, clinical, regulatory and sales milestones up to $1.5B plus tiered royalties. Also launched Series A-3 financing led by Eisai with $24M first close. Post-announcement, SEED completed the financing as a $30M Series A-3 ($24M first close Aug 2024 + $6M second close Aug 2025) and advanced its broader RITE3 molecular-glue platform: FDA cleared the IND for internal lead ST-01156 (RBM39 degrader) in Aug 2025 and the first Phase 1 patient (NCT07197554) was dosed Jan 2026. The Eisai collaboration remains a pending option-bearing research alliance — Eisai stays a cornerstone investor/collaborator and the $1.5B in biobucks is contingent on Eisai exercising exclusive rights on the undisclosed targets, which remain preclinical.

Key facts

Related deals — scored

DealYearValueOutcome
Eisai Co., Ltd. / SEED Therapeutics Inc. (this deal)2024$1.5B
Eisai Co., Ltd. / Ligand Pharmaceuticals (oncology product portfolio)2006$205M41
Eisai Co., Ltd. / MGI Pharma Inc.2007$3.9B36
Novartis AG / Advanced Accelerator Applications S.A.2017$3.9B98
Allergan plc / Merck & Co., Inc. (CGRP receptor antagonist program)2015$250M91
Cephalon Inc. / Laboratoire L. Lafon S.A. (Group Lafon)2000$450M89
Teva Pharmaceutical Industries Ltd. / Auspex Pharmaceuticals2015$3.5B86

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