Pharma BD Deal Intelligence

AstraZeneca PLC / Rigel Pharmaceuticals, Inc. (Fostamatinib license)

2010 · Licensing/Option · $1.2B · Terminated

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Feb 16, 2010 FierceBiotech Bullish

AstraZeneca paid $100M upfront with up to $1.145B in milestones plus tiered double-digit royalties for the most advanced oral Syk inhibitor in RA —…

Feb 22, 2010 Fierce Biotech Bearish

$800 million of the $1.2 billion headline consisted of back-end sales milestones; such post-launch milestones are an old trick used by biotech executives to…

Jun 04, 2013 The Pharma Letter Bearish

AstraZeneca returned fostamatinib rights to Rigel after disappointing OSKIRA Phase 3 results in RA — retrospectively framing the original $1.245B deal as a…

Source summaries from our enrichment pipeline; follow links for originals.

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AstraZeneca/Rigel exclusive worldwide license for fostamatinib: $100M upfront + up to $345M dev/reg/first-sale milestones + up to $800M sales milestones + tiered double-digit royalties. Includes Rigel's broader Syk inhibitor portfolio.

Key facts

Related deals — scored

DealYearValueOutcome
AstraZeneca PLC / Rigel Pharmaceuticals, Inc. (Fostamatinib license) (this deal)2010$1.2B
AstraZeneca PLC / Daiichi Sankyo Company, Limited2019$6.9B100
AstraZeneca PLC / KuDOS Pharmaceuticals Limited2005$210M98
AstraZeneca PLC / Alexion Pharmaceuticals Inc.2020$39.0B86
AstraZeneca PLC / Acerta Pharma2015$4.0B86
AstraZeneca PLC / Amgen Inc.2020$2.3B84
AstraZeneca PLC / MedImmune Inc.2007$15.6B82

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