Pharma BD Deal Intelligence

AstraZeneca PLC / KuDOS Pharmaceuticals Limited

2005 · Acquisition/Merger · $210M · Complete

A $210M bolt-on for a Cambridge biotech's DNA-repair science became Lynparza — the first approved PARP inhibitor, a multi-billion-dollar franchise, and the cornerstone of AstraZeneca's oncology turnaround.

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The coverage arc

Dec 23, 2005 Citeline (Pink Sheet) Bullish

AstraZeneca acquired KuDOS for $210M cash, gaining a recognized DNA-repair / PARP inhibitor expert group and a clinical and preclinical pipeline complementing…

Jan 01, 2020 Cancer Research UK Cambridge Institute Bullish

KuDOS, founded by Steve Jackson, developed olaparib through first-in-human trials before the AstraZeneca acquisition; the program ultimately reduced disease…

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AstraZeneca acquires KuDOS for $210M; gains DNA-repair/PARP inhibitor platform - basis for olaparib (Lynparza).

Did it work? Outcome assessment

A $210M bolt-on for a Cambridge biotech's DNA-repair science became Lynparza — the first approved PARP inhibitor, a multi-billion-dollar franchise, and the cornerstone of AstraZeneca's oncology turnaround.

Strategic verdict
Achieved Stated Rationale

Key facts

Related deals — scored

DealYearValueOutcome
AstraZeneca PLC / KuDOS Pharmaceuticals Limited (this deal)2005$210M98
AstraZeneca PLC / Daiichi Sankyo Company, Limited2019$6.9B100
AstraZeneca PLC / Alexion Pharmaceuticals Inc.2020$39.0B86
AstraZeneca PLC / Acerta Pharma2015$4.0B86
AstraZeneca PLC / Amgen Inc.2020$2.3B84
AstraZeneca PLC / MedImmune Inc.2007$15.6B82
AstraZeneca PLC / CinCor Pharma Inc.2023$1.8B78

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