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AstraZeneca acquired CinCor Pharma for $1.8B for hypertension treatment.
AstraZeneca to acquire CinCor Pharma to strengthen cardiorenal pipeline with baxdrostat.
CinCor Pharma to be acquired by AstraZeneca for $26/share upfront plus $10 CVR totaling approximately $1.8 billion.
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AstraZeneca acquired CinCor Pharma in February 2023 for approximately $1.8 billion ($26.00/share upfront plus a $10.00/share contingent value right) to add baxdrostat, a first-in-class oral aldosterone synthase inhibitor, to its cardiorenal pipeline. The thesis was validated post-close: the pivotal BaxHTN Phase III trial met its primary endpoint (the 2 mg dose lowered seated systolic blood pressure by 15.7 mmHg from baseline and 9.8 mmHg vs placebo at 12 weeks), the data were published in NEJM and presented at ESC 2025, the US NDA was accepted under Priority Review on 2 December 2025, and on 18 May 2026 the FDA approved baxdrostat as BAXFENDY -- the first aldosterone synthase inhibitor for adults with hypertension inadequately controlled on other antihypertensives.
| Deal | Year | Value | Outcome |
|---|---|---|---|
| AstraZeneca PLC / CinCor Pharma Inc. (this deal) | 2023 | $1.8B | 78 |
| AstraZeneca PLC / Daiichi Sankyo Company, Limited | 2019 | $6.9B | 100 |
| AstraZeneca PLC / KuDOS Pharmaceuticals Limited | 2005 | $210M | 98 |
| AstraZeneca PLC / Alexion Pharmaceuticals Inc. | 2020 | $39.0B | 86 |
| AstraZeneca PLC / Acerta Pharma | 2015 | $4.0B | 86 |
| AstraZeneca PLC / Amgen Inc. | 2020 | $2.3B | 84 |
| AstraZeneca PLC / MedImmune Inc. | 2007 | $15.6B | 82 |
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