Pharma BD Deal Intelligence

Aptevo Therapeutics Inc. / Niowave, Inc.

2026 · Co-Development · Complete

Outcome grade pending — assessed 5 years post-close.

Full analysis, sources & comparables →

The coverage arc

May 27, 2026 healthtechnologynet.com Neutral

Aptevo contributes its multispecific antibody platforms (ADAPTIR and ADAPTIR-FLEX technologies) alongside development expertise. Niowave receives an initial…

May 27, 2026 stocktitan.net Neutral

Niowave made an at-the-market equity investment in Aptevo at closing, representing an initial ownership position of 7.9%, with the potential to build a…

May 27, 2026 tipranks.com Neutral

Aptevo Therapeutics (Nasdaq: APVO) and Niowave, Inc. announced a 50/50 strategic collaboration to develop up to three radiopharmaceutical oncology programs.…

Source summaries from our enrichment pipeline; follow links for originals.

All 6 sources with sentiment breakdown →

Aptevo Therapeutics (Nasdaq: APVO) and Niowave entered a 50/50 strategic collaboration to develop up to three radiopharmaceutical oncology programs, with the first program directed at Nectin-4 and pairing Aptevo's proprietary molecule APVO455 with Niowave's Actinium-225 and additional radioisotopes. Executed concurrently were a collaboration agreement (commencing with a proof-of-concept study), a supply agreement under which Niowave supplies radioisotopes to Aptevo, and a stock purchase agreement. At closing Niowave made an at-the-market equity investment giving it an initial ~7.9% ownership position (based on shares outstanding as of May 13, 2026), with the potential to build to up to 19.99% through warrant exercises at a premium and future purchases of Aptevo common stock. No transaction dollar value was disclosed.

Key facts

Related deals — scored

DealYearValueOutcome
Aptevo Therapeutics Inc. / Niowave, Inc. (this deal)2026
AstraZeneca PLC / Daiichi Sankyo Company, Limited2019$6.9B100
Novartis AG / Endocyte, Inc.2018$2.1B96
Astellas Pharma Inc. / Seagen Inc.2009$4.5B95
Bristol-Myers Squibb Company / Medarex Inc.2009$2.4B92
Servier / Agios Pharmaceuticals (oncology)2020$2.0B91
Servier Pharmaceuticals LLC / Agios Pharmaceuticals Inc.2020$2.0B91

Compare all 7 side-by-side →

See the full interactive analysis, sources & comparables →