Pharma BD Deal Intelligence

Adaptimmune Therapeutics plc / GlaxoSmithKline plc

2016 · Co-Development · $500M · Complete

WRONG BY 70 POINTS

Not actually an acquisition — a GSK cell-therapy licensing bet that GSK later reversed entirely, handing the asset back to Adaptimmune after exiting the modality

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Top 25 most overhyped deals we track

Ranks computed across 828 graded deals (Critic + Outcome Score both present).

The coverage arc

Feb 02, 2016 Adaptimmune Therapeutics Bullish

Expanded agreement could yield ~$500M in NY-ESO development milestones; GSK effectively funds the pivotal synovial sarcoma studies and shares combination-study…

Feb 03, 2016 GEN (Genetic Engineering & Biotechnology News) Neutral

GSK and Adaptimmune expand their cancer immunotherapy collaboration, with up to eight proof-of-principle combination studies including checkpoint inhibitors…

Jul 23, 2018 GSK Media Bullish

GSK confirmed full transition of the NY-ESO SPEAR T-cell programme from Adaptimmune, taking sole responsibility for development and commercialization following…

Source summaries from our enrichment pipeline; follow links for originals.

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Adaptimmune and GSK expanded their June 2014 strategic collaboration to accelerate development of NY-ESO SPEAR T-cell therapy toward registration trials in synovial sarcoma and exploration in MRCLS. Under the expanded terms, Adaptimmune was eligible for up to ~$500M in incremental development milestones for NY-ESO program alone if GSK exercised its option and successfully developed in multiple indications/HLA types. GSK retained option rights pending Phase 1 data review.

Did it work? Outcome assessment

Not actually an acquisition — a GSK cell-therapy licensing bet that GSK later reversed entirely, handing the asset back to Adaptimmune after exiting the modality

Strategic verdict
Failed to Achieve

Key facts

Related deals — scored

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Astellas Pharma Inc. / Seagen Inc.2009$4.5B95
Bristol-Myers Squibb Company / Medarex Inc.2009$2.4B92
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