Pharma BD Deal Intelligence

Otsuka Pharmaceutical Co., Ltd. / Avanir Pharmaceuticals, Inc.

2014 · Acquisition/Merger · $3.5B · Complete

CALLED IT — OFF BY 22
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The coverage arc

Dec 03, 2014 BioSpace Neutral

Deal positioned as Otsuka's largest US acquisition, anchoring its post-Abilify CNS strategy alongside Rexulti and Samsca.

Dec 03, 2014 Zacks/Nasdaq Analyst Blog Bullish

Avanir shares jumped on a 13.3% premium offer; analysts noted Nuedexta's $74.2M nine-month sales (+47% YoY) and AVP-786's late-stage potential as the value…

Dec 08, 2014 C&EN (American Chemical Society) Bearish

EP Vantage cautioned the steep valuation rests on AVP-786 succeeding in Alzheimer's agitation — a regulatory pathway 'no easier than the currently approved…

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Otsuka agreed to acquire Avanir Pharmaceuticals for $17.00 per share, valuing the company at approximately $3.5B. Deal added Nuedexta for pseudobulbar affect and the late-stage AVP-786 program for Alzheimer's agitation, completing Otsuka's transformation toward a global CNS pharma. Closed Q1 2015.

Did it work? Outcome assessment

Strategic verdict
Failed to Achieve
Financial impact
Impaired/Written Down
Pipeline outcome
Assets Terminated

Key facts

Related deals — scored

DealYearValueOutcome
Otsuka Pharmaceutical Co., Ltd. / Avanir Pharmaceuticals, Inc. (this deal)2014$3.5B41
Otsuka Pharmaceutical Co., Ltd. / Transcend Therapeutics, Inc.2026$1.2B
Otsuka Pharmaceutical Co., Ltd. / 4D Molecular Therapeutics, Inc.2025$421M
Otsuka Pharmaceutical Co., Ltd. / Cantargia AB2025$613M
Otsuka Pharmaceutical Co., Ltd. / Jnana Therapeutics Inc.2024$1.1B
Novartis AG / Advanced Accelerator Applications S.A.2017$3.9B98
Allergan plc / Merck & Co., Inc. (CGRP receptor antagonist program)2015$250M91

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