Pharma BD Deal Intelligence

Novartis AG / Argo Biopharmaceutical Co., Ltd.

2025 · Licensing/Option · $5.3B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Sep 03, 2025 Argo Biopharma (Company IR) Bullish

Argo will receive an upfront payment of $160 million and is eligible for potential milestone and option payments of up to $5.2 billion, plus tiered royalties.…

Sep 03, 2025 Fierce Biotech Bullish

Novartis is once again turning to Argo Biopharma, this time handing over $60 million upfront and up to $5.2 billion in biobucks for a multi-asset…

Sep 03, 2025 pharmaphorum Neutral

Novartis pens $5.2bn cardiovascular partnership with Argo, paying $160 million upfront for an R&D alliance covering multiple cardiovascular siRNA drugs.

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Novartis expanded its collaboration with Argo Biopharma for multiple cardiovascular siRNA assets - the third transaction between the parties. Argo receives $160M upfront, up to $5.2B in milestone and option payments, and tiered royalties. Includes an option on ex-China rights to two discovery-stage molecules for severe hypertriglyceridemia / mixed dyslipidemia, a right of first negotiation on BW-00112 (ANGPTL3, Phase 2), and a license to an additional IND-enabling hepatic siRNA. Novartis also signaled a non-binding intention to join Argo's next equity financing round.

Key facts

Related deals — scored

DealYearValueOutcome
Novartis AG / Argo Biopharmaceutical Co., Ltd. (this deal)2025$5.3B
Novartis AG / Advanced Accelerator Applications S.A.2017$3.9B98
Novartis AG / Endocyte, Inc.2018$2.1B96
Novartis AG / Lek Pharmaceuticals d.d.2002$876M88
Novartis AG / GlaxoSmithKline plc2014$16.0B81
Novartis AG / PTC Therapeutics Inc.2024$2.9B80
Novartis AG / Chinook Therapeutics Inc.2023$3.5B78

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