Pharma BD Deal Intelligence

Merck & Co. Inc. / Endocyte, Inc.

2012 · Co-Development · $1.0B · Terminated

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Apr 16, 2012 Merck & Co. Bullish

"Vintafolide is a promising and innovative late-stage cancer drug candidate...This agreement underscores our strategy of building a portfolio of oncology…

Nov 27, 2012 Merck & Co. Bullish

"The acceptance of the EMA filing for vintafolide is an important milestone for Merck and Endocyte," said Gary Gilliland, oncology franchise head, Merck…

May 05, 2014 American Journal of Managed Care (AJMC) Bearish

Coverage of PROCEED halt noted the trial failure came just over a month after EMA's positive conditional approval opinion, making the reversal especially…

Source summaries from our enrichment pipeline; follow links for originals.

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Merck-Endocyte exclusive worldwide agreement on vintafolide. $120M upfront, up to $880M in dev/reg/commercial milestones across 6 cancer indications. 50/50 US profit share, double-digit ex-US royalty. Phase 3 PROCEED trial in platinum-resistant ovarian cancer.

Key facts

Related deals — scored

DealYearValueOutcome
Merck & Co. Inc. / Endocyte, Inc. (this deal)2012$1.0B
Merck & Co. Inc. / Acceleron Pharma Inc.2021$11.5B90
Merck & Co. Inc. / Peloton Therapeutics Inc.2019$2.2B88
Merck & Co. Inc. / AstraZeneca PLC2017$8.5B87
Merck & Co. Inc. / Moderna, Inc.2022$250M86
Merck & Co. Inc. / Moderna, Inc.2016$250M84
Merck & Co. Inc. / Eisai Co., Ltd.2018$5.8B83

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