Pharma BD Deal Intelligence

Johnson & Johnson / Synthes Inc.

2011 · Acquisition/Merger · $19.7B · Complete

A $19.7B acquisition that made J&J a leader in orthopedic trauma devices, folding Synthes's implant portfolio into its medical device arm—yet the tie-up delivered only partial returns, with integration friction and financial performance falling well short of the deal's strategic promise.

CALLED IT — OFF BY 2

J&J / Synthes: Partially Achieved (Score: 47/100)

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The coverage arc

Jan 08, 2003 Wikipedia Neutral

J&J acquired Synthes for $19.7B for orthopedic implants and trauma devices.

Jun 11, 2012 Federal Trade Commission Neutral

FTC puts conditions on Johnson & Johnsons proposed acquisition of Synthes, requiring J&J to sell its system for surgically treating serious wrist fractures.

Jun 14, 2012 Johnson & Johnson Bullish

Johnson & Johnson completed the acquisition of Synthes, Inc. on June 14, 2012 for a total purchase price of $19.7 billion in cash and stock, creating the…

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J&J acquired Synthes for $19.7B for orthopedic implants and trauma devices.

Did it work? Outcome assessment

J&J / Synthes: Partially Achieved (Score: 47/100)

Strategic verdict
Partially Achieved

Key facts

Disease & market context

Orthopedic Trauma & Spine

7M US cases/yr · $28.0B Global Orthopedic Implant Market (2011) · $3.97B Synthes Global Sales (2011)

Disease Overview

Synthes was the global leader in orthopedic trauma fixation and spinal implants with $3.97B in 2011 sales. J&J's $19.7B acquisition created DePuy Synthes, the world's largest orthopedic company with >70% US wrist fracture market share.

Post-Deal Impact

DePuy Synthes became J&J's largest MedTech division ($9.2B revenue by 2024). Growth challenged by pricing pressure and competition from Stryker/Zimmer Biomet. In 2025, J&J announced plans to spin off DePuy Synthes.

Deal timeline

Related deals — scored

DealYearValueOutcome
Johnson & Johnson / Synthes Inc. (this deal)2011$19.7B77
Johnson & Johnson / Legend Biotech Corporation2017$9.0B96
Johnson & Johnson / Centocor Inc.1999$4.9B92
Johnson & Johnson / Cougar Biotechnology, Inc.2009$970M91
Johnson & Johnson / Actelion Ltd2017$30.0B90
Johnson & Johnson / Aragon Pharmaceuticals Inc.2013$1.0B89
Johnson & Johnson / Legend Biotech Corporation2017$350M83

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