Pharma BD Deal Intelligence

GSK plc / Suzhou Siran Biotechnology Co., Ltd.

2026 · Licensing/Option · $1.1B · Complete

CALLED IT — OFF BY 8

Phase 1 siRNA in-license expanding GSK cardiometabolic reach

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May 06, 2026 BioSpace Neutral

GSK goes beyond weight-loss with $1B deal for Chinese siRNA specialist SiranBio (SA-030, ALK7).

May 06, 2026 pharmaphorum Neutral

GSK bolts on siRNA drug from China's SiranBio in $1bn deal.

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On May 6, 2026, GSK and Suzhou Siran Biotechnology (SiranBio) announced an exclusive worldwide license agreement (excluding mainland China, Hong Kong, Macau and Taiwan) for SA-030 (SA030), a potentially first-in-disease, long-acting small interfering RNA (siRNA) oligonucleotide targeting activin receptor-like kinase 7 (ALK7) for metabolic and vascular (cardiometabolic) disease, with an obesity/abdominal-fat-reduction angle. GSK pays $55 million upfront and up to ~$1.005 billion in development, regulatory, and commercial milestones, plus tiered royalties. SiranBio will advance SA-030 through completion of Phase 1, after which GSK assumes development, regulatory filings, and commercialization outside the excluded regions.

Key facts

Related deals — scored

DealYearValueOutcome
GSK plc / Suzhou Siran Biotechnology Co., Ltd. (this deal)2026$1.1B55
GSK plc / SmithKline Beecham2000$12.0B79
GSK plc / Pfizer Inc.2018$0.0M77
GSK plc / Novartis AG2014$16.0B76
GSK plc / Hansoh Pharmaceutical Group Co. Ltd.2023$1.7B74
GSK plc / Nuvalent, Inc.2026$10.6B70
GSK plc / Sierra Oncology Inc.2022$1.9B70

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