Pharma BD Deal Intelligence

GSK plc / Merck KGaA

2019 · Co-Development · $4.2B · Terminated

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Ranks computed across 828 graded deals (Critic + Outcome Score both present).

The coverage arc

Sep 30, 2021 Fierce Biotech Bearish

GSK's $4.2B bet on Merck KGaA's cancer drug goes up in smoke as pharmas cut ties.

Oct 01, 2021 BioSpace Bearish

GSK and Merck KGaA break up their $4 billion oncology collaboration after multiple clinical trial failures of bintrafusp alfa, ending a partnership that had…

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GSK and Merck KGaA formed a global immuno-oncology alliance to co-develop and co-commercialize bintrafusp alfa (M7824), a bifunctional TGF-beta trap/anti-PD-L1 fusion protein. GSK paid EUR 300M upfront with up to EUR 500M in development milestones and EUR 2.9B in approval/commercial milestones. The collaboration was terminated September 2021 after multiple clinical trial failures.

Key facts

Related deals — scored

DealYearValueOutcome
GSK plc / Merck KGaA (this deal)2019$4.2B29
GSK plc / SmithKline Beecham2000$12.0B79
GSK plc / Pfizer Inc.2018$0.0M77
GSK plc / Novartis AG2014$16.0B76
GSK plc / Hansoh Pharmaceutical Group Co. Ltd.2023$1.7B74
GSK plc / Nuvalent, Inc.2026$10.6B70
GSK plc / Sierra Oncology Inc.2022$1.9B70

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