Pharma BD Deal Intelligence

GSK plc / Jiangsu Hengrui Pharmaceuticals Co. Ltd.

2025 · Licensing/Option · $12.0B · Complete

CALLED IT — OFF BY 15
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Top 25 largest deals of the 2020s

Ranks computed across 828 graded deals (Critic + Outcome Score both present).

The coverage arc

Jul 28, 2025 BioPharma Dive Bullish

GSK will pay Hengrui $500 million upfront to start the alliance. In return, it will receive rights outside of the greater China region and Taiwan to an…

Jul 28, 2025 STAT News Bullish

GSK said Monday it would pay $500 million upfront for rights to an experimental COPD drug from Jiangsu Hengrui Pharmaceuticals, the latest example of a pharma…

Sep 05, 2025 Chemical & Engineering News Neutral

A Jefferies report found one-third of pharma licensing deal spending in H1 2025 involved China-originated drugs, up from 21% in prior years, raising…

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GSK licensed a potential best-in-class PDE3/4 inhibitor HRS-9821 for COPD from Hengrui Pharma, plus agreements to develop up to 11 additional programs across respiratory, immunology/inflammation, and oncology. GSK paid $500M upfront for the PDE3/4 program. Total potential value up to ~$12B if all programs are optioned and all milestones achieved. Hengrui leads development through Phase 1 completion.

Key facts

Related deals — scored

DealYearValueOutcome
GSK plc / Jiangsu Hengrui Pharmaceuticals Co. Ltd. (this deal)2025$12.0B65
GSK plc / SmithKline Beecham2000$12.0B79
GSK plc / Pfizer Inc.2018$0.0M77
GSK plc / Novartis AG2014$16.0B76
GSK plc / Hansoh Pharmaceutical Group Co. Ltd.2023$1.7B74
GSK plc / Nuvalent, Inc.2026$10.6B70
GSK plc / Sierra Oncology Inc.2022$1.9B70

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