Pharma BD Deal Intelligence

Enodia Therapeutics / Kezar Life Sciences

2026 · Asset Purchase · $128M · Complete

Enodia Therapeutics acquired Kezar Life Sciences' Sec61-based discovery and development program, comprising preclinical assets and associated datasets from Kezar's Sec61 translocon research. Kezar received a $1 million upfront payment and is eligible for future payments on achievement of certain development, regulatory and commercialization milestones for a potential total of up to $127 million, plus tiered royalties on net sales (rates undisclosed). The transaction covered only the Sec61 program; Kezar retained zetomipzomib, its clinical-stage selective immunoproteasome inhibitor then in evaluation for autoimmune hepatitis. The acquired program consolidated Enodia's Sec61 portfolio ahead of its October 2026 Sec61 research collaboration and license agreement with Pfizer.

This deal is too recent to grade. Critic Score and Outcome Score are assigned after the announcement-week coverage settles and, for Outcome, after the 5-year post-close assessment window opens — expected 2031 at the earliest for this deal, once/if it closes.

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