Pharma BD Deal Intelligence

Bristol-Myers Squibb Company / Philochem AG

2025 · Licensing/Option · $1.4B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Jun 16, 2025 BioPharma Dive Bullish

Bristol Myers Squibb's RayzeBio unit will pay up to $1.35 billion to license a prostate cancer radioligand therapy from Swiss biotech Philochem, the company…

Jun 16, 2025 Reuters Neutral

Bristol Myers Squibb's RayzeBio unit said on Monday it would license a prostate cancer radioligand therapy from Swiss biotech Philochem in a deal worth up to…

Jun 17, 2025 MedCity News Bullish

Bristol Myers Squibb's radiopharmaceuticals subsidiary RayzeBio is licensing global rights to Philochem's OncoACP3, designed for both diagnostic imaging and…

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BMS's RayzeBio unit licensed global rights to Philochem's OncoACP3, a small-molecule ligand targeting acid phosphatase 3 (ACP3) for radioligand therapy and imaging of prostate cancer, for $350M upfront and up to $1B in development, regulatory and commercial milestones plus mid-single to low double-digit royalties on global net sales. Differentiated from PSMA-targeting Pluvicto. The deal closed on August 18, 2025 following U.S. FTC clearance under the Hart-Scott-Rodino Antitrust Improvements Act; RayzeBio leads development and any commercialization. A Phase I 68Ga-OncoACP3 imaging study (NCT06840535) reached primary completion in late 2025, with an Actinium-225 therapeutic variant (225Ac-OncoACP3) advancing toward clinical testing in 2026.

Key facts

Related deals — scored

DealYearValueOutcome
Bristol-Myers Squibb Company / Philochem AG (this deal)2025$1.4B
Bristol-Myers Squibb Company / Medarex Inc.2009$2.4B92
Bristol-Myers Squibb Company / Celgene Corporation2019$74.0B77
Bristol-Myers Squibb Company / MyoKardia Inc.2020$13.1B76
Bristol-Myers Squibb Company / Karuna Therapeutics2023$14.0B76
Bristol-Myers Squibb Company / Ono Pharmaceutical Co., Ltd.201176
Bristol-Myers Squibb Company / SystImmune Inc.2023$8.4B71

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