Pharma BD Deal Intelligence

Bristol-Myers Squibb Company / Five Prime Therapeutics

2014 · Co-Development · Complete

WRONG BY 34 POINTS

Not actually an acquisition — a 2014 BMS/Five Prime checkpoint discovery collaboration whose flagship follow-on asset (cabiralizumab) failed Phase 2 in 2020 and was shelved; BMS never owned Five Prime, which was later bought by Amgen for an unrelated drug.

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The coverage arc

Nov 24, 2014 Drug Development & Delivery Neutral

Trade coverage reports the exclusive clinical collaboration to evaluate the combination of investigational immunotherapies Opdivo and FPA008 in six tumor…

Oct 01, 2015 Genetic Engineering & Biotechnology News Bullish

GEN reported BMS expanded the original 2014 clinical collaboration into a $1.74B license ($350M upfront, $1.05B oncology milestones per product), framing it as…

Feb 19, 2020 MedCity News Bearish

MedCity News reported Five Prime shares fell 10% on the failure announcement, and BMS stated it had 'no near-term plans for additional sponsored development of…

Source summaries from our enrichment pipeline; follow links for originals.

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BMS and Five Prime entered an exclusive Phase 1a/1b clinical-collaboration agreement to evaluate cabiralizumab (FPA008, anti-CSF-1R) combined with Opdivo across six tumor types. Strategically notable as foundation for Five Prime's eventual $1.9B 2015 expanded oncology pact and Amgen's acquisition of Five Prime in 2021.

Did it work? Outcome assessment

Not actually an acquisition — a 2014 BMS/Five Prime checkpoint discovery collaboration whose flagship follow-on asset (cabiralizumab) failed Phase 2 in 2020 and was shelved; BMS never owned Five Prime, which was later bought by Amgen for an unrelated drug.

Strategic verdict
Failed to Achieve

Key facts

Related deals — scored

DealYearValueOutcome
Bristol-Myers Squibb Company / Five Prime Therapeutics (this deal)201423
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Bristol-Myers Squibb Company / Ono Pharmaceutical Co., Ltd.201176
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