Pharma BD Deal Intelligence

Angelini Pharma S.p.A. / Catalyst Pharmaceuticals, Inc.

2026 · Acquisition/Merger · $4.1B · Complete

Outcome grade pending — assessed 5 years post-close.

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The coverage arc

Feb 26, 2025 globenewswire.com Neutral

Catalyst Pharmaceuticals Reports Record Fourth Quarter and Full Year 2024 Financial Results. Full Year 2024 Total Revenues of $491.7 Million, Marking Another…

May 07, 2026 biopharmadive.com Neutral

Angelini to buy Catalyst in $4B play for rare neuro drugs. The acquisition reflects broader pharma momentum in CNS therapeutics, with multiple major players…

May 07, 2026 sec.gov Neutral

Catalyst Pharmaceuticals, Inc. announced that it entered into a definitive merger agreement with Angelini Pharma S.p.A. under which Angelini Pharma agreed to…

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Angelini Pharma agreed to acquire all outstanding shares of Catalyst Pharmaceuticals for $31.50 per share in cash, a total equity value of approximately $4.1 billion (€3.5 billion). The price is a 21% premium to Catalyst's unaffected April 22, 2026 closing price (28% vs. its 30-day VWAP). The all-cash deal is structured as a one-step merger (via Angelini Cielo Inc.) subject to a Catalyst stockholder vote and HSR antitrust clearance, with an expected close in Q3 2026; there is no financing condition. The acquisition marks Angelini's entry into the U.S. market and adds Catalyst's commercial rare-neurological franchise (FIRDAPSE, AGAMREE, FYCOMPA) to Angelini's brain-health platform. Financing is via cash and debt, with BNP Paribas as sole global coordinator/underwriter and Blackstone funds participating as co-investors. A Catalyst termination fee of approximately $155.5 million applies in specified circumstances. Concurrent with the deal, Catalyst settled its last FIRDAPSE generic patent litigation (with Hetero), pushing generic amifampridine entry no earlier than January 2035 and reinforcing the durability of its lead franchise.

Key facts

Related deals — scored

DealYearValueOutcome
Angelini Pharma S.p.A. / Catalyst Pharmaceuticals, Inc. (this deal)2026$4.1B
Novartis AG / Advanced Accelerator Applications S.A.2017$3.9B98
Allergan plc / Merck & Co., Inc. (CGRP receptor antagonist program)2015$250M91
Cephalon Inc. / Laboratoire L. Lafon S.A. (Group Lafon)2000$450M89
Teva Pharmaceutical Industries Ltd. / Auspex Pharmaceuticals2015$3.5B86
Teva Pharmaceutical Industries Ltd. / Biogal Pharmaceutical199582
Novartis AG / PTC Therapeutics Inc.2024$2.9B80

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